Once again, science is cool.
After about 70 nanoseconds the ball arrives at home plate. The batter hasn’t even seen the pitcher let go of the ball, since the light carrying that information arrives at about the same time the ball does. Collisions with the air have eaten the ball away almost completely, and it is now a bullet-shaped cloud of expanding plasma (mainly carbon, oxygen, hydrogen, and nitrogen) ramming into the air and triggering more fusion as it goes. The shell of x-rays hits the batter first, and a handful of nanoseconds later the debris cloud hits.
Read the full, awesome description in all its physics glory here. Worth the time.